The Relevance Of Clodronate Liposome In Medical Science

By Roxanne Cruz


Medical science, being one of the most fascinating field in the industry has found different solutions to different problems over time. Before, yellow fever for example killed thousands of residents in different areas. But because of the discoveries of the assiduous medical scientists, yellow fever vaccine was invented. Clodronate liposome is one of those outstanding discoveries that will play a great role in the field of medicine.

Clodronate also known as clodronate disodium and clodronic acid is a first generation non nitrogenous bisphosphonate. It is a drug scientifically approved, tested, and used to prevent and treat the cases of osteoporosis especially to the women who have reached the post menopausal period. It is also used in the experimental medicine to deplete macrophages.

These are white blood cells within tissues. Macrophages are produced by the division of the white blood cells formed in the bone marrow and spleen. These kind of white blood cell is known to be as monocytes which ingest foreign particles after it was formed. Basically, macrophage is the core of the system which fight against infectious viruses and diseases.

In cell biology, liposomes are the tiny bubble which are composed of fatty sacs with liquid inside. These are used in both research and experiment in cell biology. It is filled with drugs that are used to cure cancer and different diseases. It is filled with liquid and phospholipids.

Medical science discovered clodronate liposome that will function in the suppression of macrophages. It is known to be the fighter against microorganism. Aside from defending the body from the organisms that will infect and impair the system, it can also be the source of the disease.

In normal circumstances, a healthy immune system will help in dealing with sickness such as colds, fever and coughs. They functions as the defender from illnesses and diseases. On the other way around, a damaged one will result to your own cells attacking the healthy cells. When this happens, various severe medical disorders will affect the body.

As mentioned earlier, immune response protects the body from viral invasion. However, several damages will lead to grave autoimmune medical conditions caused by transplant rejection. This transplant rejection is one of the effects of the response. As a new organ in places on the transplant patient, cells will incite the system to attack the organ cells that will lead to rejection.

Because of these cases that will damage the body defense against harmful organisms, doctors and scientists fumbled upon the discovery of liposome. This medicine is made of bisphosphonate that will help lessen the quantity of macrophage. As soon as macrophage detects that this drug transported inside the body is foreign, it will automatically engulf it whole through phagocytosis.

This discovery marked a significance in the history of medicine industry. Not only that the cancers will be treated, other diseases will be as well. However, even though clodronate liposome is reported to help treat cancer and many other illnesses, consult your own doctor first. This is to ensure your health will not be at risk. Ask prescriptions from your doctor if you could have one.




About the Author: